Latest medical research, by specialty

Every week Web of Medicine reads the new papers in Q1 journals for each specialty and keeps the ones that matter to practising clinicians. Each list gives you the top studies of the week and a paper of the day, with a short summary and an Oxford CEBM evidence level for every study. Updated 22 September 2026.

• Anatomy

  This week's top study: CT-FFR in stable CAD: A meta-analysis of clinical outcomes and healthcare cost

• Anesthesiology and Pain Medicine

  This week's top study: Comparison of liposomal bupivacaine and modified cocktail analgesia for postoperative pain control after transforaminal lumbar interbody fusion: a prospective, double-blind, randomized controlled trial

• Bariatric and Metabolic Surgery

  This week's top study: Beyond Weight Reduction: An Updated Systematic Review and Meta-Analysis of Metabolic Syndrome Components and Metabolic Dysfunction-Associated Steatotic Liver Disease Outcomes After Endoscopic Sleeve Gastroplasty

• Biochemistry (medical)

  This week's top study: Efficacy of efruxifermin in improving liver fibrosis in patients with metabolic dysfunction-associated steatohepatitis/nonalcoholic steatohepatitis: a systematic review and meta-analysis of randomized controlled trials

• Breast and Endocrine Surgery

  This week's top study: Short or Long Antibiotic Regimens in Orthopedics

• Cardiology and Cardiovascular Medicine

  This week's top study: Effectiveness of SGLT2 inhibitors in slowing chronic kidney disease progression and reducing mortality: a meta-analysis

• Complementary and Alternative Medicine

  This week's top study: Moxibustion combinations for diabetic peripheral neuropathy: a network meta-analysis of 40 randomised trials

• Critical Care and Intensive Care Medicine

  This week's top study: Early Versus Late Tracheostomy: An Umbrella Review and Meta-Analysis

• Dermatology

  This week's top study: Sentinel lymph node biopsy in melanoma: Redundant in the neoadjuvant era

• Emergency Medicine

  This week's top study: Superior-head automated external defibrillator placement during single-rescuer cardiopulmonary resuscitation: a randomized crossover simulation study and retrospective multicenter cohort

• Epidemiology

  This week's top study: Menopause hormone therapy and type 2 diabetes risk and prognosis: systematic review and meta-analyses

• Family Practice

  This week's top study: Effectiveness of high-dose versus standard-dose influenza vaccines against hospitalisation according to frailty risk: a prespecified analysis of the randomised trial DANFLU-2

• Gastroenterology

  This week's top study: Colonoscopy Intervals and Colorectal Cancer Incidence after Adenoma Removal

• Gastrointestinal and Colorectal Surgery

  This week's top study: Single-stapled versus double-stapled colorectal anastomosis after anterior resection: Systematic review and meta-analysis of short-term and functional outcomes

• Health Informatics

  This week's top study: Modifiers of effectiveness and deterioration, and prognostic factors of adherence in internet-based interventions for treatment of perinatal depression: A systematic review and individual participant data meta-analysis

• Hematology

  This week's top study: Blinatumomab for Replacing Chemotherapy in Pediatric Acute Lymphoblastic Leukemia

• Histology

  This week's top study: Efficacy of efruxifermin in improving liver fibrosis in patients with metabolic dysfunction-associated steatohepatitis/nonalcoholic steatohepatitis: a systematic review and meta-analysis of randomized controlled trials

• Internal Medicine

  This week's top study: Effects of continuing or withholding angiotensin axis blockers prior to elective surgery: The PAAB randomized clinical trial

• Medical Physics

  This week's top study: Cost-utility of NeuroSAFE-guided RARP Versus Standard RARP in Men with Localised Prostate Cancer in the UK

• Microbiology (medical)

  This week's top study: Treatment shortening and relapse control in drug-susceptible pulmonary tuberculosis: a network meta-analysis of randomized trials

• Neonatology

  This week's top study: Association between surgical repair timing and mortality in neonates with congenital diaphragmatic hernia: a systematic review and meta-analysis

• Nephrology

  This week's top study: Effectiveness of SGLT2 inhibitors in slowing chronic kidney disease progression and reducing mortality: a meta-analysis

• Neurology (clinical)

  This week's top study: Factor XIa Inhibitors for Secondary Prevention After Noncardioembolic Stroke: A Systematic Review and Meta-Analysis

• Obstetrics and Gynecology

  This week's top study: Association Between Proteinuria and Pregnancy Outcomes in Women With Preterm Pre-Eclampsia Undergoing Expectant Management: Secondary Analysis of Two Randomised Trials

• Oncology and Radiation Oncology

  This week's top study: Pembrolizumab plus chemotherapy as first-line therapy for advanced HER2-negative gastric or gastroesophageal junction adenocarcinoma: 4.5-year follow-up from the randomized phase III KEYNOTE-859 study

• Ophthalmology

  This week's top study: Safety and Efficacy of Brolucizumab in the Treatment of Patients with Diabetic Macular Edema and Diabetic Retinopathy: A Systematic Review and Meta-Analysis

• Orthopedics and Sports Medicine

  This week's top study: Quality-of-life outcomes and osteoarthritis development at 10-years after anterior cruciate ligament reconstruction: A large randomized clinical trial comparing patellar tendon, hamstring tendon and double-bundle grafts

• Otorhinolaryngology

  This week's top study: Prophylactic Home-Based Exercises During Radiotherapy in Head and Neck Cancer: A Randomized Controlled Trial

• Pathology and Forensic Medicine

  This week's top study: Chronic endometritis in women undergoing in vitro fertilization: Diagnostic roles of hysteroscopy and endometrial biopsy and associations with reproductive outcomes - A systematic review and meta-analysis

• Pediatric Surgery

  This week's top study: Association between surgical repair timing and mortality in neonates with congenital diaphragmatic hernia: a systematic review and meta-analysis

• Pediatrics and Child Health

  This week's top study: Evaluating the Role of School-Based Weekly Iron-Folic Acid Supplementation in Shaping Common Morbidity and Growth Outcomes Among Adolescent Girls: Evidence From a Cluster-Randomized Controlled Trial in Central Ethiopia Region

• Pharmacology (medical)

  This week's top study: Effectiveness of SGLT2 inhibitors in slowing chronic kidney disease progression and reducing mortality: a meta-analysis

• Psychiatry and Mental Health

  This week's top study: Lumateperone as Adjunctive Therapy in Patients With Major Depressive Disorder and Anxious Distress: Post Hoc Analysis of a Phase 3, Randomized, Double-Blind Trial

• Pulmonary and Respiratory Medicine

  This week's top study: A Multicenter Randomized Phase III Trial Comparing MET Tyrosine Kinase Inhibitors vs. Immune Checkpoint Inhibitors With or Without Chemotherapy as First-Line Treatment for Patients With Advanced Non-Small Cell Lung Cancer Harboring MET Exon 14 Skipping Mutations: JCOG2506 (DECIDE-MET)

• Radiation Oncology

  This week's top study: Summary of Research: HER2CLIMB-05: A Phase III Study of Tucatinib Versus Placebo in Combination with Trastuzumab and Pertuzumab as First-Line Maintenance Therapy for HER2+ Metastatic Breast Cancer

• Radiology, Radiation Oncology, Nuclear Medicine, Medical Physics and Imaging

  This week's top study: Radiation Therapy for Bladder Cancer: An ASTRO Clinical Practice Guideline

• Rehabilitation

  This week's top study: Effect of Sequential Electroacupuncture Combined With Augmented Reality Gait Training on Walking Function and Neuromuscular Control in Subacute Stroke: A Randomized Controlled Trial

• Rheumatology

  This week's top study: Impact of Dual Interleukin-17A and Interleukin-17F Inhibition with Bimekizumab on Inflammatory and Structural Lesions in Axial Spondyloarthritis: MRI and Radiographic Outcomes from the Phase 3 BE MOBILE 1 and 2 Studies and their Open-Label Extension

• Surgery

  This week's top study: The application value of Da Vinci linear powered stapler SureForm in robotic sphincter-preserving surgery for rectal cancer: a prospective randomized clinical trial

• Surgical Oncology

  This week's top study: Sentinel lymph node biopsy in melanoma: Redundant in the neoadjuvant era

• Transplantation

  This week's top study: Evaluation of eculizumab for the prevention of delayed graft function after kidney transplantation in adults: A randomized, double-blind, placebo-controlled trial

• Urology

  This week's top study: Clinical outcomes of selective dorsal cryoneurolysis in patients with lifelong premature ejaculation: a retrospective cohort of 108 men

Looking for a topic rather than new papers? Browse the evidence summaries.