Latest Microbiology (medical) research

Top 10 this week

Week of 20 September 2026

1. 1

   Treatment shortening and relapse control in drug-susceptible pulmonary tuberculosis: a network meta-analysis of randomized trials

   Frontiers in cellular and infection microbiology · Q1 journal · SR/MA of RCTs · Evidence level 1 (High) · 3 September 2026

   Not directly related to diagnostic microbiology

2. 2

   Efficacy and safety of fecal microbiota transplantation for chronic constipation: a systematic review and meta-analysis integrating pre-post and single-arm evidence

   Frontiers in microbiology · Q1 journal · SR/MA of RCTs · Evidence level 1 (High) · 3 September 2026

   FMT for constipation, not relevant to diagnostic microbiology

3. 3

   Effects of gut microbiota-targeted interventions on pain, physical function, and inflammatory biomarkers in osteoarthritis: a systematic review and meta-analysis of randomized controlled trials

   Frontiers in cellular and infection microbiology · Q1 journal · SR/MA of RCTs · Evidence level 1 (High) · 4 September 2026

   Gut‑targeted interventions in osteoarthritis

4. 4

   COVID-19 vaccine effectiveness in people on immunosuppressive therapies: a systematic review and meta-analysis

   The Lancet. Microbe · Q1 journal · SR/MA of RCTs · Evidence level 1 (High) · 15 September 2026

   High-quality evidence in a top journal

5. 5

   Duration of effectiveness of tuberculosis preventive treatment across various tuberculosis burden settings: a systematic review and individual-participant meta-analysis

   The Lancet. Respiratory medicine · Q1 journal · SR/MA of RCTs · Evidence level 1 (High) · 18 September 2026

   TB preventive treatment duration review, not diagnostic focus

6. 6

   Gut microbiome dysbiosis, short-chain fatty acid depletion and implications for neuroinflammation in atypical parkinsonian syndromes - a systematic review of patient cohorts

   Journal of Parkinson's disease · Q1 journal · SR/MA of RCTs · Evidence level 1 (High) · 17 September 2026

   Gut microbiome in Parkinson, unrelated to diagnostics

7. 7

   Examining the multidimensional implications of oral health in chronic kidney disease: A systematic review

   Journal of the American Dental Association (1939) · Q2 journal · SR/MA of RCTs · Evidence level 1 (High) · 17 September 2026

8. 8

   Antibiotic pretreatment and culture yield in pediatric osteoarticular infection: a systematic review and meta-analysis

   Clinical and experimental pediatrics · Q1 journal · SR/MA of RCTs · Evidence level 1 (High) · 14 September 2026

   Antibiotic pretreatment effect on culture yield in pediatric osteoarticular infection

9. 9

   Economic evaluation of enhanced oral care in reducing the incidence of non-ventilator hospital-acquired pneumonia

   The Journal of hospital infection · Q1 journal · RCT · Evidence level 1 (High) · 16 September 2026

   Economic evaluation of oral care, not microbiology

10. 10

    Cefoxitin versus cefotaxime as empirical treatment of spontaneous bacterial peritonitis in liver cirrhotic patients: randomized controlled clinical trial

    The Journal of antimicrobial chemotherapy · Q1 journal · RCT · Evidence level 1 (High) · 1 September 2026

    Cefoxitin vs cefotaxime SBP trial, not microbiology diagnostics

Paper of the day, last two weeks

• International epidemiology of antimicrobial resistance in people living with chronic lung infection

  Thorax · Q1 journal · Cohort · Evidence level 3 (Low) · 21 September 2026

  Large AMR surveillance across CF and bronchiectasis

• Molecular based diagnostic testing for urinary tract infections: the results remain unclear

  World journal of urology · Q1 journal · SR/MA of RCTs · Evidence level 1 (High) · 20 September 2026

  In two recent randomized trials of 773 mostly older women, PCR-based testing was more sensitive than standard culture and led to faster symptom improvement over 28 days. However, the tests lacked specificity and most studies were funded by the manufacturers, so larger independent trials are needed before routine adoption.

• Early Prediction of Carbapenem Resistance in Gram-Negative Organisms at Culture Ordering from Routinely Collected Hospital Data: Temporal and External Validation of ORDER-CARB

  Infectious diseases and therapy · Q1 journal · Prospective cohort · Evidence level 2 (Moderate) · 17 September 2026

  ORDER‑CARB model predicts carbapenem resistance at culture order

• A randomized controlled trial evaluating a novel individualized treatment strategy for carbapenem-resistant Gram-negative bacteria infections

  International journal of antimicrobial agents · Q1 journal · RCT · Evidence level 1 (High) · 17 September 2026

  iACT‑guided therapy trial for carbapenem‑resistant infections

• Amplicon-based nanopore sequencing for Mycobacterium spp. identification in clinical isolates and sputum

  International journal of medical microbiology : IJMM · Q1 journal · Unclassified · Evidence level 5 (Expert Opinion) · 10 September 2026

  Myco‑ANS nanopore assay for Mycobacterium spp. identification

• Temporal trends and mortality associated with difficult-to-treat resistance in bloodstream gram-negative bacilli: a retrospective cohort study in Southern Saudi Arabia

  Frontiers in cellular and infection microbiology · Q1 journal · Retrospective cohort · Evidence level 3 (Low) · 31 August 2026

  Escalating carbapenem resistance, DTR linked to mortality

• Behavioural antimicrobial stewardship interventions in outpatient settings: a systematic review and meta-analysis of physician-targeted approaches

  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · Q1 journal · SR/MA of RCTs · Evidence level 1 (High) · 12 September 2026

• Automated microbial recognition from gram-stained micrographs via CNN and metadata decision support

  Frontiers in cellular and infection microbiology · Q1 journal · Prospective cohort · Evidence level 2 (Moderate) · 28 August 2026

  CNN‑based automated species identification from Gram‑stained images

• Sonication versus peri-implant tissue culture in fracture-related infection: diagnostic performance and therapeutic consequences in a single-center cohort

  Journal of bone and joint infection · Q1 journal · Retrospective cohort · Evidence level 3 (Low) · 26 August 2026

  Sonication vs peri‑implant tissue culture in fracture‑related infection

• Sonication versus peri-implant tissue culture in fracture-related infection: diagnostic performance and therapeutic consequences in a single-center cohort

  Journal of bone and joint infection · Q1 journal · Retrospective cohort · Evidence level 3 (Low) · 26 August 2026

  Sonication vs peri‑implant tissue culture in fracture‑related infection

• Mapping Wastewater Pathogens and Their Associated Environmental and Public Health Risk Factors: A Systematic Review and Meta-Analysis

  International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · Q1 journal · SR of cohorts · Evidence level 2 (Moderate) · 8 September 2026

  Systematic review of wastewater pathogen surveillance

• Integrating metagenomic next-generation sequencing into a multimodal diagnostic framework for spinal infection: enhancing etiological identification and clinical prediction

  Frontiers in cellular and infection microbiology · Q1 journal · Retrospective cohort · Evidence level 3 (Low) · 24 August 2026

  mNGS integrated into multimodal spinal infection diagnostics

• Urine-Blood Culture Concordance in Suspected Urosepsis and Implications for Early Clinical Decision-Making

  International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · Q1 journal · Cohort · Evidence level 3 (Low) · 3 September 2026

  In a review of 2,572 adult urosepsis episodes, urine and blood cultures shared the same pathogen in 55% of cases, and urine results were available within one day for half of the patients. When concordant, urine susceptibility testing closely mirrored blood results and was linked to quicker inflammation decline and improved survival, suggesting urine culture can guide early therapy while blood results await.