Latest Medical Physics research
The 10 most useful medical physics studies published this week, chosen from Q1 journals and graded on the Oxford CEBM evidence hierarchy. Each paper links to a short summary and the original on PubMed. Updated 22 September 2026.
Top 10 this week
Week of 20 September 2026
- 1
Cost-utility of NeuroSAFE-guided RARP Versus Standard RARP in Men with Localised Prostate Cancer in the UK
European urology open science · Q1 journal · RCT · Evidence level 1 (High) · 9 September 2026
In a trial of 407 men, the nerve-sparing NeuroSAFE technique added about £800 in NHS costs and improved quality-adjusted life expectancy by 0.03 QALYs, yielding an incremental cost-effectiveness ratio of roughly £26,000 per QALY. The result sits near the upper UK willingness-to-pay threshold, but considerable uncertainty remains, especially beyond the 12-month follow-up.
- 2
Low-Dose Radiation Therapy (LDRT) for Osteoarthritis: A Retrospective Study of 94 Patients and 136 Joints Treated
Advances in radiation oncology · Q1 journal · RCT · Evidence level 1 (High) · 21 May 2026
In a retrospective series of 94 older adults (average age 74) treated on 136 joints, six fractions of 0.5 Gy lowered the average pain score from 7.3 to 2.6 on a 0-10 scale. Nearly four-fifths achieved a clinically meaningful improvement, regardless of age, sex or joint size, suggesting a safe, non-invasive option pending confirmatory trials.
- 3
Delivered-Dose Validation of Nonadaptive Diagnostic Computed Tomography-Based Volumetric Modulated Arc Therapy for Simulation-Free Palliative Radiation Therapy
Practical radiation oncology · Q1 journal · Retrospective cohort · Evidence level 3 (Low) · 16 September 2026
In a retrospective study of 30 plans, the delivered dose on first-fraction cone-beam CT was 99.6% of the planned dose on diagnostic CT, with all treatments achieving at least 97% of the intended coverage. Target coverage and organ-at-risk doses were preserved across spinal and pelvic sites, supporting wider use of simulation-free VMAT in palliative care.
- 4
Monte Carlo intercomparison of TG-43 dosimetric parameters for clinical192Ir and125I brachytherapy sources
Physics in medicine and biology · Q1 journal · Unclassified · Evidence level 5 (Expert Opinion) · 15 September 2026
Monte Carlo intercomparison of TG‑43 parameters for 192Ir and 125I
- 5
A Modular Multi-Agent Reinforcement Learning Framework Guided by LLMs: Improving Quality and Efficiency of Treatment Planning in Lung Radiotherapy
International journal of radiation oncology, biology, physics · Q1 journal · Unclassified · Evidence level 5 (Expert Opinion) · 17 September 2026
Hybrid LLM‑RL framework improves lung IMRT planning efficiency
- 6
Measurement-anchored Monte Carlo prediction of diagnostic x-ray air kerma using HVL-matched spectra and per-electron normalization
Medical physics · Q1 journal · Unclassified · Evidence level 5 (Expert Opinion) · 1 October 2026
Measurement‑anchored Monte Carlo prediction of x‑ray air kerma
- 7
Beyond the snapshot: continuous optical surface monitoring reveals non-linear temporal dynamics and postural stability window in free-breathing breast radiotherapy
Frontiers in oncology · Q2 journal · Cohort · Evidence level 3 (Low) · 3 September 2026
- 8
Real-time tumor tracking for magnetic resonance-guided radiotherapy using label-efficient foundation model adaptation
Physics and imaging in radiation oncology · Q1 journal · Unclassified · Evidence level 5 (Expert Opinion) · 10 September 2026
MedSAM2 adaptation enables real‑time cine‑MRI tumor tracking
- 9
Highly Accelerating Joint Intracranial and Carotid Vessel Wall Imaging Using ESPIRiT-Driven Diffusion Model Reconstruction
Magnetic resonance in medicine · Q1 journal · Unclassified · Evidence level 5 (Expert Opinion) · 14 September 2026
ESPIRiT‑Driven diffusion reconstruction for accelerated vessel wall imaging
- 10
Inter-crystal scatter recovery of a light-sharing depth-encoding Prism-PET prototype scanner using a diffusion model
Medical physics · Q1 journal · Unclassified · Evidence level 5 (Expert Opinion) · 1 September 2026
Inter‑crystal scatter recovery for Prism‑PET prototype, diffusion model
Paper of the day, last two weeks
Comparative Efficacy of Acupuncture, Pharmacological Interventions, Sham Acupuncture, and Placebo for Migraine Prevention: A Bayesian Network Meta-Analysis
Pain research & management · Q1 journal · SR/MA of RCTs · Evidence level 1 (High) · 1 January 2026
Clinical implementation and evaluation of an artificial intelligence-driven one-click automatic planning system for functional lung avoidance radiotherapy
Practical radiation oncology · Q1 journal · Unclassified · Evidence level 5 (Expert Opinion) · 16 September 2026
One-click auto-planning reduces planning time, dosimetric evaluation
First Implementation of an All-in-One Solution With Fully Automatic Workflow for Rectal Cancer Based on an Integrated CT-linac
Practical radiation oncology · Q1 journal · Prospective cohort · Evidence level 2 (Moderate) · 14 September 2026
95. Early outcomes showed a 15% complete response rate and 68% of surgical patients had near-complete tumor regression, while leukopenia occurred in 55%. Larger trials are needed to confirm efficacy and safety.
A combined dose and microdosimetric modeling framework incorporating volume effects correlates with tissue sparing in proton minibeam radiotherapy
International journal of radiation oncology, biology, physics · Q1 journal · Unclassified · Evidence level 5 (Expert Opinion) · 13 September 2026
A new dose-microdosimetric model showed that proton minibeam radiotherapy lowers normal tissue complication probability compared with conventional homogeneous fields, especially when the peak-to-valley dose ratio is greater than 15 and organ seriality is around 0.7. The effect is strongest at shallow depths and aligns with prior experimental trends, suggesting that incorporating microdosimetry and tissue architecture could guide future clinical optimization.
Predicting the benefit of adaptive radiotherapy in head and neck Cancer using cone-beam computed tomography
Physics and imaging in radiation oncology · Q1 journal · Unclassified · Evidence level 5 (Expert Opinion) · 21 August 2026
CBCT dose differences predict adaptive RT benefit
Quality assurance for deep learning-based proton therapy planning in routine clinical use for oropharyngeal cancer
Physics and imaging in radiation oncology · Q1 journal · Unclassified · Evidence level 5 (Expert Opinion) · 20 August 2026
A standardized measurement-based approach to estimate modelled relative biological effectiveness for auditing carbon ion beams
Physics and imaging in radiation oncology · Q1 journal · Unclassified · Evidence level 5 (Expert Opinion) · 17 August 2026
Measurement‑based RBE estimation for carbon ion beams
Cherenkov-excited fluorescence imaging for small-field dosimetry and SRS plan verification: a feasibility study
Physics in medicine and biology · Q1 journal · Unclassified · Evidence level 5 (Expert Opinion) · 10 September 2026
Cherenkov fluorescence small-field dosimetry
Dose-Registered CT assessment of radiation-induced lung injury after chemoradiotherapy for stage III NSCLC
Annals of medicine · Q1 journal · Retrospective cohort · Evidence level 4 (Very Low) · 10 September 2026
Dose‑registered CT analysis of radiation‑induced lung injury
A lightweight deep learning model for automated segmentation of Gynecologic organs and cervical Tumors on T2-weighted magnetic resonance imaging
Physics and imaging in radiation oncology · Q1 journal · Unclassified · Evidence level 5 (Expert Opinion) · 24 July 2026
Lightweight DL model for automated cervical MRI segmentation
Learning-enhanced hybrid planar-SPECT dosimetry for voxel-level Monte Carlo dose estimation in radionuclide therapy
Physics in medicine and biology · Q1 journal · Unclassified · Evidence level 5 (Expert Opinion) · 7 September 2026
Hybrid planar‑SPECT framework for voxel‑level MC dose
Impact of collimator misalignments on dosimetric robustness in proton minibeam radiotherapy using an automated measurement setup
Medical physics · Q1 journal · Unclassified · Evidence level 5 (Expert Opinion) · 1 September 2026
Collimator misalignment impact on proton minibeam dosimetry
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For healthcare professionals. Summaries are generated by AI from the published abstract and are not medical advice. Read the original paper before changing practice.