Enhanced swallowing function and quality of life in post-stroke dysphagia: superior efficacy of tongue-nape acupuncture combined with tDCS
- Journal
- Topics in stroke rehabilitation (Q1)
- Published
- 4 September 2026
- Study design
- Unclassified
- Evidence level
- Level 5, Expert Opinion (CEBM 5)
- Authors
- Na Liang, Yang Xue, Qi Pan, Wenzhen Shi, Xin Lei, Xuewei Li, et al.
- PMID
- 42695205
- DOI
- 10.1080/10749357.2026.2723407
Why clinicians should know about it
- Picked for Complementary and Alternative Medicine (paper of the day, 7 September 2026): Acupuncture + tDCS improves post‑stroke dysphagia
- Picked for Rehabilitation (paper of the day, 7 September 2026): Tongue‑nape acupuncture + tDCS improves post‑stroke dysphagia
Abstract
BACKGROUND: This study evaluated the combined effects of Tongue-Nape Acupuncture (TNA) and Transcranial Direct Current Stimulation (tDCS) on 85 post-stroke dysphagia (PSD) patients. METHODS: Participants were assigned to either a tDCS-only group (n = 40) or a TNA + tDCS group (n = 45). Swallowing function (Water Swallowing Test, Standard Swallowing Assessment) and Quality of Life (QoL) were assessed. Serum levels of neural injury markers (S-100β, NSE, MMP-9, Hcy, hs-CRP) were measured, alongside brain activity (near-infrared imaging) and muscle function (EMG). RESULTS: The TNA + tDCS group achieved significantly greater improvements in swallowing scores and a higher overall clinical response rate (91.1% vs. 77.5%) compared to the tDCS-only group (p < 0.05). The combination therapy led to significant reductions in neural injury biomarkers and increased oxyhemoglobin concentrations in sensorimotor and prefrontal areas, indicating positive neurobiological changes and enhanced brain activity. EMG results also showed improved muscle function and coordination in the combined group. No significant difference in adverse reactions was observed between groups. In addition, serum biomarker assay results demonstrated that, post-intervention, the combination group exhibited significantly decreased levels of S-100β, NSE, MMP-9, homocysteine, and high-sensitivity C-reactive protein, indicating benign neurobiological alterations. CONCLUSION: The study concludes that combining TNA and tDCS is a promising strategy for improving swallowing and feeding functions, enhancing QoL, and offering potential neuroprotective benefits for patients with PSD.
Abstract as published, via PubMed.
For healthcare professionals. The summary is generated by AI from the published abstract, and the evidence level is assigned automatically from the study design on the Oxford CEBM hierarchy. Neither is medical advice. Read the full paper before changing practice.