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The effect of eye patching on sclerostomy wound architecture in 25-gauge sutureless pars plana vitrectomy: A randomized controlled trial

Journal
Indian journal of ophthalmology (Q2)
Published
24 August 2026
Study design
Randomized controlled trial
Evidence level
Level 1, High (CEBM 1b)
Authors
Nur Shahirah Amir Hamzah, Ainal Adlin Naffi, Mushawiathi Mustapha, Mae-Lynn Catherine Bastion
PMID
42635453
DOI
10.4103/IJO.IJO_2876_25

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  • Picked for Ophthalmology (top studies of the week, 30 August 2026): High-quality evidence in a top journal

Abstract

PURPOSE: To investigate the effects of postoperative eye patching on the sclerostomy wound architecture in 25-gauge sutureless pars plana vitrectomy (PPV). DESIGN: Single-blind prospective randomized controlled trial. METHODS: Twenty-eight subjects who underwent 25-gauge sutureless PPV were randomly assigned to either the intervention group (n = 14) or the control group (n = 14). The intervention group received postoperative eye patching for approximately 24 hours, whereas the control group received an eye shield. The sclerostomy wound architecture was examined postoperatively at day 1, week 1, and month 1 using anterior segment optical coherence tomography. RESULTS: The outer diameter of the sclerotomy wound in the intervention group was generally smaller than in the control group: day 1 (194.0 [IQR: 51] μm vs 107.5 [IQR: 44] μm, P = 0.285), week 1 (69.1 ± 18.4 μm vs 72.8 ± 26.1 μm, P = 0.667), and month 1 (44.2 ± 12.0 μm vs 52.9 ± 13.6 μm, P = 0.086). A similar difference was also observed in the inner diameter: day 1 (78.5 [IQR: 45] μm vs 85.0 [IQR: 121] μm, P = 0.946), week 1 (71.0 [IQR: 32] μm vs 63.0 [IQR: 42] μm, P = 0.874), and month 1 (44.2 ± 12.0 μm vs 53.0 ± 13.6 μm, P = 0.086). However, the result was not statistically significant. CONCLUSION: Postoperative eye patching facilitates scleral healing and has a role in protecting the scleral wound during the vulnerable immediate postoperative period. It demonstrated better healing characteristics of the wound compared to the control group.

Abstract as published, via PubMed.

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For healthcare professionals. The summary is generated by AI from the published abstract, and the evidence level is assigned automatically from the study design on the Oxford CEBM hierarchy. Neither is medical advice. Read the full paper before changing practice.