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Early spine surgery is associated with better outcomes in patients with a thoracic spinal cord injury: national database retrospective analysis

Journal
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society (Q1)
Published
5 November 2026
Study design
Unclassified
Evidence level
Level 5, Expert Opinion (CEBM 5)
Authors
Maor Shir, Ariel Sacknovitz, Moshe Serwatien, Ayla Weiss, Merritt D Kinon, John V Wainwright
PMID
42983053
DOI
10.1007/s00586-026-10399-0

Why clinicians should know about it

  • Picked for Spine Surgery (paper of the day, 8 November 2026): Thoracic spinal cord injury surgery timing and outcomes

Abstract

INTRODUCTION: We aim to determine whether early surgery (within 24 h of admission) is associated with better discharge disposition in patients with isolated and polytraumatic thoracic SCI. METHODS: Patients in the Trauma Quality and Improvement Database from 2017 to 2023 presenting with a thoracic SCI and underwent surgical intervention were collected based on Abbreviated Injury Scale (AIS) codes and ICD-10 procedural codes. Polytrauma was determined as those patients presenting with an AIS ≥ 3 in a body region not associated with thoracic SCI and GCS < 14. Propensity score matching (PSM) was conducted to match early and late surgery groups for isolated SCI and polytrauma separately. Univariate analysis was conducted to determine differences in hospital complications and disposition. Multivariate logistic regression for disposition was modelled. Multivariate regression using the propensity matched data with a 3-level time to surgery variable (< 8 h, 8-24 h, 24 + hours) was modelled. RESULTS: After PSM there were 4,524 isolated and 2,842 polytrauma thoracic SCI patients. The isolated and polytrauma SCI group with early surgery had lower rates of hospital complications. Isolated SCI patients with late surgery had 22% (95% CI: 4%-42%) higher odds of poor disposition. Polytrauma patients with late surgery had 42% (95% CI: 18%-70%) higher odds of poor disposition. Isolated thoracic SCI patients undergoing surgery 8-24 h after admission had a 32% (95% CI: 4%-68%) increase in odds of poor disposition compared to those undergoing surgery within 8 h of admission. CONCLUSION: Early surgery in patients presenting with an isolated thoracic SCI or polytrauma with thoracic SCI was associated with more positive discharge dispositions.

Abstract as published, via PubMed.

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For healthcare professionals. The summary is generated by AI from the published abstract, and the evidence level is assigned automatically from the study design on the Oxford CEBM hierarchy. Neither is medical advice. Read the full paper before changing practice.