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Cartilage Support with Alar Groove Reconstruction for Nasal Deformity in Hemifacial Atrophy: A Multicenter Prospective Study

In brief

In hemifacial atrophy, surgery reduced alar asymmetry from 8.7 to 1.1 mm

In this single-arm study, 84 patients followed for 12 to 36 months had improved nasal symmetry after cartilage grafting and reconstruction of the grooves around the nostril; average alar base asymmetry fell from 8.7 mm to 1.1 mm. Nasal obstruction scores also improved, but without a comparison group, the technique's advantage over other approaches remains unknown.

Journal
Aesthetic plastic surgery (Q1)
Published
9 October 2026
Study design
Prospective / inception cohort
Evidence level
Level 2, Moderate (CEBM 2b)
Authors
Yang Hu, Chengwu Zhang, Chao Li, Jingjie Qiao, Yang Wang, Ping Li, et al.
PMID
42855506
DOI
10.1007/s00266-026-06302-3

Why clinicians should know about it

Abstract

BACKGROUND: Nasal alar deformity in hemifacial atrophy is challenging due to combined loss of structural support and surface landmarks. Existing techniques usually address either volumetric deficiency or framework reinforcement alone. This study evaluates a strategy integrating autologous cartilage support with simultaneous reconstruction of the supra-alar and alar-facial grooves. METHODS: In this prospective multicenter study, consecutive patients with hemifacial atrophy and unilateral alar collapse with groove attenuation or obliteration underwent standardized surgical correction (subcutaneous release, autologous cartilage grafting, and multi-point traction suturing). Outcomes were assessed using standardized two-dimensional photographic morphometric analysis and the validated Nasal Obstruction Symptom Evaluation scale. RESULTS: Among 91 enrolled patients, 84 completed follow-up for 12 to 36 months. Significant improvements were observed in objective alar symmetry, including reduction in alar base asymmetry from 8.72 ± 0.99 mm preoperatively to 1.12 ± 0.49 mm postoperatively (P < 0.001) and nostril width discrepancy from 6.22 ± 0.87 mm to 0.74 ± 0.38 mm (P < 0.001). Apparent two-dimensional photographic parameters of supra-alar and alar-facial groove morphology demonstrated sustained improvement in groove definition and continuity among patients with available longitudinal data. Functional outcomes improved, with NOSE scores decreasing from 68.4 ± 12.6 preoperatively to 17.4 ± 7.5 at final follow-up (P < 0.001). The overall complication rate was low, and no major revision surgery was required. CONCLUSIONS: This single-arm prospective cohort suggests that cartilage support combined with alar groove reconstruction is a feasible approach for selected patients with hemifacial atrophy and may provide sustained improvements in alar symmetry and surface landmark definition. Because of the absence of a comparative control group, these findings should be interpreted as preliminary, and further comparative studies are required to confirm the relative effectiveness of this technique. LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Abstract as published, via PubMed.

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For healthcare professionals. The summary is generated by AI from the published abstract, and the evidence level is assigned automatically from the study design on the Oxford CEBM hierarchy. Neither is medical advice. Read the full paper before changing practice.