Skip to main content

Postoperative pulmonary complications after totally thoracoscopic cardiac surgery: a retrospective cohort study comparing single-lumen and double-lumen endotracheal tubes

Journal
Frontiers in medicine (Q1)
Published
16 September 2026
Study design
Prospective / inception cohort
Evidence level
Level 2, Moderate (CEBM 2b)
Authors
Rongquan Chen, Zhijin Hu, Yan Lin, Xiaoying Wu, Binlian Liu, Wenqing Zhang
PMID
42819475
DOI
10.3389/fmed.2026.1928907

Why clinicians should know about it

Abstract

OBJECTIVE: Double-lumen tubes (DLTs) are standard for one-lung ventilation in totally thoracoscopic cardiac surgery but are associated with airway injury and postoperative pulmonary complications (PPCs). This study compared perioperative outcomes between single-lumen tube (SLT)-based and DLT-based strategies in 176 adults undergoing elective totally thoracoscopic cardiac surgery (SLT, n = 94; DLT, n = 82). METHODS: This was a single-center retrospective cohort study. The SLT-based strategy employed a single-lumen tube with two-lung ventilation supplemented by brief, controlled intermittent lung collapse when enhanced surgical exposure was required, whereas the DLT-based strategy employed a double-lumen tube with one-lung ventilation throughout the main phase of surgery. The primary outcome was PPC incidence; secondary outcomes included airway complications and recovery metrics. Multivariable and sensitivity analyses were performed. RESULTS: Baseline characteristics were balanced. The anesthesia-to-incision time was shorter in the SLT group (57 vs. 67 min; P < 0.001). The SLT group had lower PPC incidence [29% vs. 56%; adjusted odds ratio (aOR), 0.30; 95% CI, 0.16-0.58], including lower rates of respiratory infection (7% vs. 22%) and atelectasis (18% vs. 39%). Airway complications were also less frequent (23% vs. 48%; aOR, 0.35; 95% CI, 0.18-0.68). Mechanical ventilation duration (17.5 vs. 21.0 h; P = 0.009) and ICU stay (28.0 vs. 36.0 h; P < 0.001) were shorter in the SLT group. CONCLUSION: An SLT-based strategy was associated with improved perioperative efficiency, fewer pulmonary and airway complications, and faster recovery. These findings warrant further investigation in prospective studies.

Abstract as published, via PubMed.

View on PubMedFull text at the publisherOpen in the app

For healthcare professionals. The summary is generated by AI from the published abstract, and the evidence level is assigned automatically from the study design on the Oxford CEBM hierarchy. Neither is medical advice. Read the full paper before changing practice.