Outcomes of pediatric urgent-start peritoneal dialysis: a single-center experience from Jordan
In brief
Over half of children started on urgent peritoneal dialysis were dialysis-free after one year
In a Jordanian center, 18 kids began urgent-start peritoneal dialysis within two weeks of catheter placement; 16 had acute kidney injury. One year later, 9 of the 16 AKI patients (56%) were off dialysis, while 4 (25%) had died and 3 remained on therapy. Early complications occurred in one-quarter, highlighting both feasibility and notable risk in resource-limited settings.
- Journal
- Renal failure (Q1)
- Published
- 21 September 2026
- Study design
- Cohort / observational study
- Evidence level
- Level 3, Low (CEBM 3b)
- Authors
- Doaa Al Qaoud, Anas Haifawi, Walla Al-Qaoud, Ala'a Al-Ma'aiteh, Tamara Kufoof, Mohamad Rasoul Alrashaideh, et al.
- PMID
- 42768298
- DOI
- 10.1080/0886022X.2026.2731668
Why clinicians should know about it
- Picked for Pediatrics and Child Health (paper of the day, 24 September 2026): Urgent-start peritoneal dialysis outcomes in children with AKI
Abstract
INTRODUCTION: Urgent-start peritoneal dialysis (USPD) provides kidney replacement therapy (KRT) for children with acute kidney injury (AKI) or stage 5 chronic kidney disease (CKD) requiring dialysis. Pediatric data from resource-limited settings remain limited. METHODS: We retrospectively described 18 children who underwent USPD at a tertiary center in Jordan between January 2022 and December 2024. USPD was defined as initiation of peritoneal dialysis (PD) within 14 days of catheter insertion. Early complications occurred within 14 days of the first PD exchange, and late complications thereafter. RESULTS: Sixteen children had AKI, and two had stage 5 CKD. Etiologies were hemolytic uremic syndrome (6/18, 33.3%) and acute tubular necrosis (4/18, 22.2%). Thirteen (72.2%) initiated PD within 24 h: five at 4-12 h and eight at 24 h. Six developed early complications: a leak on 4/18 (22.2%) and an exit-site infection on 2/18 (11.1%), without overlap. Five developed late complications. Peritonitis affected 4/18 (22.2%) and accounted for five episodes; other late events included a leak in two children, an exit-site complication in one, and catheter obstruction in one, with overlapping categories. At one year, 9/16 children with AKI (56.3%) were no longer receiving dialysis, 3/16 (18.8%) remained on PD, and 4/16 (25.0%) had died. Of the two children with stage 5 CKD, one remained on hemodialysis, and one was dialysis-free after transplantation. CONCLUSIONS: This descriptive, single-center experience on USPD delivery, complications, and one-year outcomes. The small sample, absence of a comparator group, and heterogeneity preclude conclusions about safety, timing effects, or predictors.
Abstract as published, via PubMed.
For healthcare professionals. The summary is generated by AI from the published abstract, and the evidence level is assigned automatically from the study design on the Oxford CEBM hierarchy. Neither is medical advice. Read the full paper before changing practice.