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Thoracoscopic Patch Repair of Large Congenital Diaphragmatic Hernia Defects is Safe and Associated with Low Recurrence Rate

Journal
Journal of pediatric surgery (Q1)
Published
21 September 2026
Study design
Cohort / observational study
Evidence level
Level 3, Low (CEBM 3b)
Authors
Marta Gazzaneo, Athanasios Tyraskis, Laura Privitera, Stefano Giuliani, Dhanya Mullassery, Sonia Basson, et al.
PMID
42767334
DOI
10.1016/j.jpedsurg.2026.163451

Why clinicians should know about it

  • Picked for Pediatric Surgery (paper of the day, 22 September 2026): Thoracoscopic patch repair of large CDH defects

Abstract

BACKGROUND: Thoracoscopic patch repair of congenital diaphragmatic hernia (CDH) remains challenging for large defects, with no consensus on optimal patch fixation technique. This study evaluates outcomes of thoracoscopic patch repair stratified by defect size and suturing technique and compares them with primary thoracoscopic repair. METHODS: A retrospective review was performed of CDH patients undergoing thoracoscopic repair at a single tertiary centre (2019-2025). Primary outcomes were operative time and recurrence, stratified by defect size and suturing technique (interrupted vs. running), with secondary comparison with primary thoracoscopic repair. RESULTS: Of 63 patients undergoing thoracoscopic CDH repair, 46(73%) had patch repair; 39(61.9%) were completed thoracoscopically (conversion rate 11.1%). Among patients receiving a patch 69.2%(27/39) had type C or D defects. Mean operative time was 154.4±33.5 minutes. Type D defects were associated with significantly longer operative times than type B (189±25 vs. 142±24 minutes; p = 0.03). Recurrence occurred in 3/39(7.7%) patients at a mean follow-up of 17 months; no significant association with defect size was identified (p > 0.99). Suturing technique did not significantly influence operative time (interrupted vs. running: 164±33 vs.153 ± 33 minutes; p = 0.39) or recurrence (1.4%vs.3.8% at quadrant-level analysis; p > 0.05). Recurrence rates were comparable between thoracoscopic patch and primary repair groups (7.7%vs.5.9%; p > 0.99). CONCLUSIONS: Thoracoscopic patch repair of large CDH defects is feasible. Operative times and recurrence rate were comparable between suturing techniques. Larger multicentre studies are needed to validate these findings.

Abstract as published, via PubMed.

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For healthcare professionals. The summary is generated by AI from the published abstract, and the evidence level is assigned automatically from the study design on the Oxford CEBM hierarchy. Neither is medical advice. Read the full paper before changing practice.