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Does an alar ligament tubercle exist? Anatomical study with application to imaging interpretation and skull base approaches

Journal
Neurosurgical review (Q1)
Published
18 September 2026
Study design
Unclassified
Evidence level
Level 5, Expert Opinion (CEBM 5)
Authors
Nilo Alvarez Toledo, Carmine Antonio Donofrio, Filippo Badaloni, Antonio Fioravanti, David Ezra, Noritaka Komune, et al.
PMID
42754767
DOI
10.1007/s10143-026-04489-2

Why clinicians should know about it

  • Picked for Anatomy (paper of the day, 20 September 2026): Alar ligament tubercle prevalence and morphology study

Abstract

Although numerous anatomical and radiological studies describe a "tubercle" of the alar ligaments at the medial OC as the alar ligament insertion, no systematic osteological investigation has evaluated the prevalence, morphology, and variability of this structure. Therefore, this study aimed to determine whether an alar ligament tubercle (ALT) is a consistent anatomical feature or a morphological variant. Two hundred fifty adult skulls were examined. The presence, morphology, and laterality of the ALTs were documented. Tubercle dimensions were measured using microcalipers, and a classification system was developed to detail their anatomy. High-resolution inferior-view photographs were used to outline the OCs and corresponding ALTs, and ImageJ was used to calculate the proportion of OC surface area occupied by the ALT. An ALT was identified in eight (3.2%), occurring bilaterally in seven specimens and unilaterally in one. Three morphological types were observed: small (≤ 3 mm), large (> 3 mm), and irregular/spicule-like forms. The tubercles occasionally extended to the anterior foramen magnum margin. The mean ALT dimensions were length 4.1 mm, width 3.4 mm, and thickness 4.0 mm. Five tubercles were classified as type 1 (33.3%), four as type 2 (26.7%), and six as type 3 (40.0%). The ALT occupied 10-24% (mean 15%) of the OC surface area. The ALT is a rare anatomical variant rather than a consistent OC landmark. Awareness of this variation could be useful for accurate radiological interpretation, avoidance of diagnostic pitfalls, and safe planning of skull base approaches involving the OC.

Abstract as published, via PubMed.

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For healthcare professionals. The summary is generated by AI from the published abstract, and the evidence level is assigned automatically from the study design on the Oxford CEBM hierarchy. Neither is medical advice. Read the full paper before changing practice.