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Virtual Reality-Based Vestibular Rehabilitation for Vestibular Migraine: A Randomized Trial

Journal
The Laryngoscope (Q1)
Published
19 August 2026
Study design
Randomized controlled trial
Evidence level
Level 1, High (CEBM 1b)
Authors
Gulce Kirazli, Hale Uzumcugil, Sumeyye Kapusizoglu, Ece Cinar, Huseyin Nezih Ozdemir, Gulsum Saruhan Durmaz, et al.
PMID
42618982
DOI
10.1002/lary.70814

Why clinicians should know about it

  • Picked for Otorhinolaryngology (top studies of the week, 23 August 2026): VR added to home rehab lowers DHI and improves LOS

Abstract

OBJECTIVES: To evaluate whether virtual reality-based vestibular rehabilitation (VR-VestRehab) added to home-based vestibular rehabilitation (HB-VestRehab) improves postural control, symptom severity, and psychological outcomes in vestibular migraine (VM). METHODS: This prospective, single-blind randomized controlled trial enrolled 40 patients (18-60 years) with definite VM (ICHD-3), randomized 1:1. Both groups received 4 weeks of vestibular rehabilitation; the VR-VestRehab group additionally underwent 8 clinic-based virtual reality sessions (30 min, twice weekly) using the Virtualis MotionVR system. DHI, a registered secondary outcome, was designated as the principal outcome for this report; SOT, LOS, and fHIT were the registered primary outcomes (see Methods). Other secondary outcomes were patient-reported measures (VAS, ABC, VADL, FGA, DGI, HADS). RESULTS: DHI was significantly lower in VR-VestRehab at post-treatment (p = 0.005), with a reduction exceeding the 18-point MCID; dizziness VAS was also lower (p = 0.041). LOS endpoint excursion, maximum excursion, and directional control were significantly higher in VR-VestRehab (p = 0.007, 0.003, < 0.001). In a change-score sensitivity analysis, the advantage persisted for DHI (p = 0.033), dizziness VAS (p = 0.012), and LOS directional control (p < 0.001). No between-group differences were found in SOT composite score or fHIT parameters, except right lateral canal fHIT correct-answer percentage (p = 0.019, exploratory). Both groups improved significantly within groups across nearly all measures. CONCLUSION: Adding virtual reality-based rehabilitation to home exercise provides additional benefits in symptom severity (DHI) and dynamic postural control (LOS) in vestibular migraine, while functional and psychological gains were shared by both groups. TRIAL REGISTRATION: ClinicalTrials.gov identifier: NCT07493005.

Abstract as published, via PubMed.

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For healthcare professionals. The summary is generated by AI from the published abstract, and the evidence level is assigned automatically from the study design on the Oxford CEBM hierarchy. Neither is medical advice. Read the full paper before changing practice.