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Comparison of the Efficacy of Electrical Stimulation Modalities in Treating Post-Stroke Dysphagia: A Meta-Analysis

In brief

Electrical stimulation raises long-term swallowing scores by about one point in post-stroke dysphagia

A meta-analysis of 39 trials found that electrical stimulation improved functional oral intake by roughly one level and lowered aspiration scores by about one point after four weeks or more. Neuromuscular stimulation showed the biggest long-term gains, while transcranial stimulation acted quickly; brief daily sessions (under 30 minutes) for up to three weeks were most effective.

Journal
Dysphagia (Q1)
Published
25 July 2026
Study design
Systematic review / meta-analysis of RCTs
Evidence level
Level 1, High (CEBM 1a)
Authors
Jiahui Zhu, Zhanghua Zheng
PMID
42501088
DOI
10.1007/s00455-026-10985-w

Why clinicians should know about it

  • Picked for Otorhinolaryngology (top studies of the week, 26 July 2026): Electrical stimulation for post‑stroke dysphagia, neuro‑rehab focus

Abstract

Evidence on electrical stimulation for post‑stroke dysphagia (PSD) remains inconsistent. This meta‑analysis evaluated the efficacy of neuromuscular electrical stimulation (NMES), transcranial direct current stimulation (tDCS), and peripheral electrical stimulation (PES).Randomized controlled trials (RCTs) investigating electrical stimulation therapy for patients with post-stroke dysphagia were searched in PubMed, Embase, and the Cochrane Library from inception to December 12, 2024. The primary outcomes were the Functional Oral Intake Scale (FOIS), Dysphagia Outcome and Severity Scale (DOSS), Penetration-Aspiration Scale (PAS), and Standardized Swallowing Assessment (SSA). Secondary outcomes included pharyngeal transit time (PTT), oral transit time (OTT), and surface electromyography (sEMG) signals of swallowing muscles. Meta-analysis was performed by pooling the Mean Difference (MD) with 95% confidence intervals (CI). Short‑term: <4 weeks; long‑term: ≥4 weeks.39 RCTs were included. Electrical stimulation improved short-term DOSS (MD = 1.13, 95% CI 0.15 to 2.11, P = 0.02), long-term FOIS (MD = 1.20, 95% CI 0.64 to 1.77, P < 0.01), long-term PAS (MD = -1.47, 95% CI -2.60 to -0.33, P = 0.01), and long-term SSA (MD = -0.65, 95% CI -1.28 to -0.01, P = 0.05), but not PTT or OTT. Daily treatment <30 minutes and total duration ≤3 weeks were associated with greater improvement. NMES showed stronger long‑term effects, whereas tDCS effects emerged immediately and persisted. Female proportion did not significantly affect outcomes (P > 0.05). Electrical stimulation is effective for post‑stroke dysphagia, with efficacy influenced by stimulation type and duration.

Abstract as published, via PubMed.

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For healthcare professionals. The summary is generated by AI from the published abstract, and the evidence level is assigned automatically from the study design on the Oxford CEBM hierarchy. Neither is medical advice. Read the full paper before changing practice.