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Toward Empowering Women in HIV Care: A Peer-Supported Patient-Initiated Viral Load Testing Cluster-Randomized Trial in Dar es Salaam, Tanzania

Journal
Journal of the International Association of Providers of AIDS Care (Q1)
Published
21 July 2026
Study design
Randomized controlled trial
Evidence level
Level 1, High (CEBM 1b)
Authors
Peter Karoli, Gibson B Kagaruki, Elizabeth Shayo, Ayoub Kibao, Ndeniria Swai, Zhihui Li
PMID
42478863
DOI
10.1177/23259582261471973

Why clinicians should know about it

  • Picked for Dermatology (paper of the day, 22 July 2026): Peer‑supported viral load testing in HIV care

Abstract

BackgroundRoutine viral load testing (VLT) is critical for monitoring HIV treatment effectiveness, yet adherence to annual testing and patient engagement remain suboptimal, particularly among women. We evaluated a peer educator-supported, patient-initiated VLT approach in Dar es Salaam, Tanzania.MethodsIn 2024, a two-arm cluster-randomized trial was conducted across six public HIV clinics. Intervention sites implemented a 4-6-month peer-supported program promoting patient-initiated VLT, while control sites continued routine care. Data from adult PLHIV were analyzed using regression models.ResultsAmong 567 participants, 14.8% had not tested within 12 months, with higher non-testing among men (19.7% vs. 12.2%, p=0.019). Intervention sites showed higher mean numbers tested for men (65 vs. 26) and women (146.4 vs. 57). Although patient-initiated testing was infrequent overall (2.8%), the intervention arm demonstrated higher odds of patient-initiated viral load testing than the control arm (aOR=4.69; 95% CI: 1.30-16.95).ConclusionPeer-supported strategies improved patient-initiated VLT and female engagement but require stronger health system support.

Abstract as published, via PubMed.

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For healthcare professionals. The summary is generated by AI from the published abstract, and the evidence level is assigned automatically from the study design on the Oxford CEBM hierarchy. Neither is medical advice. Read the full paper before changing practice.