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cardiologyCondition·Updated Apr 14, 2026·v1

Anticoagulation in Atrial Fibrillation

Anticoagulation in atrial fibrillation primarily utilizes direct oral anticoagulants (DOACs) to mitigate the high risk of cardioembolic stroke, requiring careful patient-specific balancing of ischemic and bleeding risks through validated scoring systems and emerging non-pharmacologic alternatives like left atrial appendage occlusion.

High Evidence75 references·3,410 words·14 min read·v1
Atrial fibrillationAnticoagulationDOACsStroke preventionCHA2DS2-VAScHAS-BLEDLeft atrial appendage occlusionReversal agentsFactor XIa inhibitors
Atrial fibrillation (AF) is the most common cardiac arrhythmia and a leading cause of cardioembolic stroke, conferring an average annual stroke risk of 4.5%. The cornerstone of mitigating this risk is systemic anticoagulation. Historically reliant on vitamin K antagonists (VKAs) like warfarin, the standard of care has definitively shifted toward direct oral anticoagulants (DOACs)—including apixaban, rivaroxaban, edoxaban, and dabigatran—due to their predictable pharmacokinetics, favorable safety profiles, and lack of routine monitoring requirements. Effective management requires a delicate balance between stroke prevention and the risk of major hemorrhage. Clinicians rely on validated risk stratification tools, such as the CHA2DS2-VASc score for ischemic risk and the HAS-BLED score for bleeding risk, though newer integrated models like the ABC and GARFIELD-AF scores are emerging. Recent guidelines emphasize holistic management pathways and personalized, shared decision-making, particularly for complex populations such as the elderly, patients with concurrent coronary artery disease, and those with recent ischemic strokes. For patients with absolute contraindications to long-term oral anticoagulation, percutaneous left atrial appendage occlusion (LAAO) offers a highly effective non-pharmacologic alternative. Meanwhile, the management of anticoagulant-related bleeding has been revolutionized by the availability of specific reversal agents, such as idarucizumab and andexanet alfa. As the global burden of AF grows with an aging population, ongoing research continues to refine therapeutic strategies, including the investigation of novel Factor XIa inhibitors designed to uncouple physiological hemostasis from pathological thrombosis, promising even safer anticoagulation paradigms in the future.

Deep Dive — Evidence Details

References

  1. [1]

    McBride D, Brüggenjürgen B, Roll S et al.. Anticoagulation treatment for the reduction of stroke in atrial fibrillation: a cohort study to examine the gap between guidelines and routine medical practice. Journal of thrombosis and thrombolysis (2007). PMID: 17260164

    L2bCOHORTCited in: Epidemiology and Stroke Risk
  2. [2]

    Wyss R, Ellis AR, Brookhart MA et al.. Matching on the disease risk score in comparative effectiveness research of new treatments. Pharmacoepidemiology and drug safety (2015). PMID: 26112690

    L5OTHERCited in: Epidemiology and Stroke Risk
  3. [3]

    Go AS, Reed GL, Hylek EM et al.. Factor V Leiden and risk of ischemic stroke in nonvalvular atrial fibrillation: the AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study. Journal of thrombosis and thrombolysis (2003). PMID: 14574075

    L5OTHERCited in: Epidemiology and Stroke Risk
  4. [4]

    Dallongeville J, Sacher F, Bouée S et al.. Xafran, a drug utilization study of rivaroxaban in stroke prevention in atrial fibrillation in France using a claim database. Therapie (2018). PMID: 30075870

    L5OTHERCited in: Epidemiology and Stroke Risk
  5. [5]

    Ariyanti D, Hibatulloh MF, Pramusinta CK et al.. The Role of CHA₂DS₂-VASc Score in Predicting Clinical Complications Following Primary Percutaneous Coronary Intervention: A Systematic Review and Meta-Analysis. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions (2025). PMID: 41047624

    L2aSR_OBSCited in: Ischemic Risk Stratification
  6. [6]

    Dorsch MP, Flynn AJ, Greer KM et al.. A Web-Based Tool to Perform a Values Clarification for Stroke Prevention in Patients With Atrial Fibrillation: Design and Preliminary Testing Study. JMIR cardio (2025). PMID: 40215398

    L1bRCTCited in: Ischemic Risk Stratification
  7. [7]

    Hammad A, Ahmad A, Khalid N et al.. Efficacy and safety of left atrial appendage occlusion for atrial fibrillation in patients with a history of prior intracranial hemorrhage: a systematic review and meta-analysis of observational studies. Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing (2026). PMID: 41026441

    L2aSR_OBSCited in: Ischemic Risk Stratification, Bleeding Risk Assessment
  8. [8]

    Tsiartas E, Samaras A, Papazoglou AS et al.. Changes in CHA2DS2-VASc score and risk of ischemic stroke among patients with atrial fibrillation. Heart and vessels (2023). PMID: 37311823

    L1bRCTCited in: Ischemic Risk Stratification
  9. [9]

    Mahawish KM, White H, Feigin V et al.. Refining predictive risk models for stroke in atrial fibrillation: a scoping review and meta-analysis for Aotearoa New Zealand, Māori and Pacific peoples. The New Zealand medical journal (2025). PMID: 40080765

    L2aSR_OBSCited in: Ischemic Risk Stratification
  10. [10]

    Ali A, Siddiqui AA, Ali M et al.. Meta-analysis on performance of ABC and GARFIELD-AF compared to CHA2DS2-VASc and HAS-BLED in anticoagulated atrial fibrillation patients. Cardiovascular revascularization medicine : including molecular interventions (2024). PMID: 37880043

    L2aSR_OBSCited in: Ischemic Risk Stratification, Bleeding Risk Assessment
  11. [11]

    Trinks-Roerdink EM, Geersing GJ, van den Dries CJ et al.. Integrated care in patients with atrial fibrillation- a predictive heterogeneous treatment effect analysis of the ALL-IN trial. PloS one (2023). PMID: 37856486

    L1bRCTCited in: Ischemic Risk Stratification
  12. [12]

    Artola Arita V, Van De Lande ME, Khalilian Ekrami N et al.. Clinical utility of the 4S-AF scheme in predicting progression of atrial fibrillation: data from the RACE V study. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology (2023). PMID: 36857318

    L2bTRIAL_NONRANDOMCited in: Ischemic Risk Stratification
  13. [13]

    Jalli E, Jaakkola J, Langén V et al.. Venous thromboembolisms and stroke risk in patients with atrial fibrillation: a nationwide cohort study. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology (2025). PMID: 40726063

    L2bCOHORTCited in: Ischemic Risk Stratification
  14. [14]

    Boettger P, Sedighi J, Piayda K et al.. Clinical implications of the recalibrated CHA₂DS₂-VA score for women after ischemic stroke: a prospective cohort study. Acta neurologica Belgica (2025). PMID: 41082160

    L2bCOHORTCited in: Ischemic Risk Stratification
  15. [15]

    Nicolas J, Dangas G, Borrow A et al.. Comparative Performance of Machine Learning and Traditional Risk Scores in Predicting Adverse Events After Transcatheter Aortic Valve Replacement in Patients With Atrial Fibrillation. The American journal of cardiology (2026). PMID: 41407062

    L1bRCTCited in: Bleeding Risk Assessment
  16. [16]

    Gerdisch MW, Garrett HE, Mumtaz MA et al.. Prophylactic Left Atrial Appendage Exclusion in Cardiac Surgery Patients With Elevated CHA2DS2-VASc Score: Results of the Randomized ATLAS Trial. Innovations (Philadelphia, Pa.) (2022). PMID: 36373654

    L1bRCTCited in: Bleeding Risk Assessment
  17. [17]

    Deng JL, He L, Jiang C et al.. [A comparison of CAS risk model and CHA2DS2-VASc risk model in guiding anticoagulation treatment in Chinese patients with non-valvular atrial fibrillation]. Zhonghua xin xue guan bing za zhi (2022). PMID: 36096706

    L1bRCTCited in: Bleeding Risk Assessment
  18. [18]

    Yang W, Hou X, Meng X et al.. [Control study of the intelligent calculation method and the traditional calculation method in risk assessments of hospitalization]. Zhonghua wei zhong bing ji jiu yi xue (2022). PMID: 35728858

    L1bRCTCited in: Bleeding Risk Assessment
  19. [19]

    Shurrab M, Austin PC, Jackevicius CA et al.. Apixaban vs rivaroxaban in patients with atrial fibrillation at high or low bleeding risk: A population-based cohort study. Heart rhythm (2025). PMID: 39154873

    L2bCOHORTCited in: Bleeding Risk Assessment
  20. [20]

    Wang W, Saczynski JS, Lessard D et al.. Presence of Geriatric Conditions Is Prognostic of Major Bleeding in Older Patients with Atrial Fibrillation: a Cohort Study. Journal of general internal medicine (2022). PMID: 35102482

    L2bCOHORTCited in: Bleeding Risk Assessment
  21. [21]

    Chao TF, Chan YH, Tuan TC et al.. Should oral anticoagulants still be prescribed to patients with atrial fibrillation with a single stroke risk factor but at high bleeding risk? A nationwide cohort study. European heart journal. Quality of care & clinical outcomes (2022). PMID: 34302335

    L2bCOHORTCited in: Bleeding Risk Assessment
  22. [22]

    Kow CS, Chen F, Jie Leong SK et al.. Bleeding risk assessment tools in patients with atrial fibrillation taking anticoagulants: a comparative review and clinical implications. Expert review of cardiovascular therapy (2025). PMID: 40550625

    L5REVIEW_NARRATIVECited in: Bleeding Risk Assessment
  23. [23]

    Yu JS, Cho MS, Kang DY et al.. Impact of Atrial Fibrillation Pattern on Edoxaban Antithrombotic Therapy in Patients With Atrial Fibrillation and Stable Coronary Artery Disease: A Secondary Analysis of the EPIC-CAD Randomized Clinical Trial. Journal of the American Heart Association (2026). PMID: 41848064

    L1bRCTCited in: Direct Oral Anticoagulants (DOACs), Management in Special Populations
  24. [24]

    Kimura K, Nishiyama Y, Iwasaki YK et al.. Catheter Ablation and Oral Anticoagulation for Secondary Stroke Prevention in Atrial Fibrillation: The STABLED Randomized Clinical Trial. JAMA neurology (2026). PMID: 41770549

    L1bRCTCited in: Direct Oral Anticoagulants (DOACs), Management in Special Populations, Perioperative and Periprocedural Management
  25. [25]

    Fasth O, Oldgren J, Ghukasyan Lakic T et al.. Early versus delayed DOAC after ischaemic stroke in atrial fibrillation: 1-year outcomes in the TIMING study and in concurrent practice. European stroke journal (2026). PMID: 41758561

    L1bRCTCited in: Direct Oral Anticoagulants (DOACs), Management in Special Populations
  26. [26]

    Al Said S, Patel SM, Giugliano RP et al.. Abelacimab vs Rivaroxaban in Older Individuals With Atrial Fibrillation: A Prespecified Analysis of the Phase 2b AZALEA-TIMI 71 Trial. JAMA cardiology (2026). PMID: 41637102

    L1bRCTCited in: Direct Oral Anticoagulants (DOACs), Management in Special Populations
  27. [27]

    Polymeris AA, Rossel JB, Koga M et al.. Once- versus twice-daily direct oral anticoagulants after ischemic stroke in atrial fibrillation - A post-hoc analysis of the ELAN trial. European stroke journal (2026). PMID: 41614485

    L1bRCTCited in: Direct Oral Anticoagulants (DOACs), Management in Special Populations
  28. [28]

    Yamanaka S, Noda T, Nochioka K et al.. Prognostic impact of systolic blood pressure and antithrombotic strategy in patients with atrial fibrillation and stable coronary artery disease: a post-hoc analysis of the AFIRE trial. Hypertension research : official journal of the Japanese Society of Hypertension (2026). PMID: 41486379

    L1bRCTCited in: Direct Oral Anticoagulants (DOACs), Management in Special Populations
  29. [29]

    Gologorsky R, Lansberg MG, Wintermark M et al.. Multiterritory Brain Infarcts, Anticoagulation, and Recurrence After Cryptogenic Stroke: A Subgroup Analysis of the ARCADIA Trial. Stroke (2026). PMID: 41347300

    L1bRCTCited in: Direct Oral Anticoagulants (DOACs)
  30. [30]

    Liang M, Jin J, Zhao R et al.. Dabigatran-based versus warfarin-based triple antithrombotic regimen with a 1-month intensification after coronary stenting in patients with nonvalvular atrial fibrillation (COACH-AF PCI). BMC medicine (2025). PMID: 41254594

    L1bRCTCited in: Direct Oral Anticoagulants (DOACs)
  31. [31]

    Siegal DM, Sticherling C, Healey JS et al.. Major Bleeding With Apixaban vs Aspirin: A Subanalysis of the ARTESiA Randomized Clinical Trial. JAMA cardiology (2025). PMID: 41222953

    L1bRCTCited in: Direct Oral Anticoagulants (DOACs)
  32. [32]

    Lee SJ, Yu HT, Lee YJ et al.. Therapy for Atrial Fibrillation in Patients with Drug-Eluting Stents. The New England journal of medicine (2026). PMID: 41211917

    L1bRCTCited in: Direct Oral Anticoagulants (DOACs)
  33. [33]

    Landmesser U, Skurk C, Kirchhof P et al.. Left Atrial Appendage Closure or Medical Therapy in Atrial Fibrillation. The New England journal of medicine (2026). PMID: 41849741

    L1bRCTCited in: Management in Special Populations
  34. [34]

    Haimovich JS, Kany S, Chang Y et al.. Incidence, Risk Factors, and Outcomes in Stressor-Associated Atrial Fibrillation: Insights From the VITAL-AF Trial. Circulation (2026). PMID: 41662456

    L1bRCTCited in: Management in Special Populations
  35. [35]

    Rivard L, Khairy P, Talajic M et al.. Anticoagulation to prevent ischemic stroke and neurocognitive impairment in atrial fibrillation: the BRAIN-AF randomized clinical trial. Nature medicine (2026). PMID: 41501492

    L1bRCTCited in: Management in Special Populations
  36. [36]

    Olsen FJ, Diederichsen SZ, Jørgensen PG et al.. Effects of Atrial Fibrillation Screening According to Echocardiographic Measures of Cardiac Structure and Function: A Post Hoc Analysis of the LOOP Randomized Clinical Trial. Journal of the American Heart Association (2026). PMID: 41467399

    L1bRCTCited in: Management in Special Populations
  37. [37]

    Younis A, Nair DG, Di Biase L et al.. Atrial Fibrillation Recurrence After Left Atrial Appendage Occlusion in Patients Undergoing Ablation: The OPTION Trial Sub analysis. JACC. Clinical electrophysiology (2026). PMID: 41201405

    L1bRCTCited in: Perioperative and Periprocedural Management
  38. [38]

    Saliba W, Nair D, Swarup V et al.. Comparison of left atrial appendage closure and oral anti-coagulation after catheter ablation for atrial fibrillation: Concomitant and sequential cohorts of the OPTION randomized controlled trial. Heart rhythm (2025). PMID: 40288474

    L1bRCTCited in: Perioperative and Periprocedural Management
  39. [39]

    Gruwez H, De Melio N, Vermunicht P et al.. Improving atrial fibrillation or flutter detection and management by smartphone-based photoplethysmography rhythm monitoring following cardiac surgery: a pragmatic randomized trial. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology (2025). PMID: 39823508

    L1bRCTCited in: Perioperative and Periprocedural Management
  40. [40]

    Ikami Y, Izumi D, Fujiki S et al.. Differences in coagulation responses to vascular injury between uninterrupted dabigatran and apixaban: A clinical prospective randomized study. Heart rhythm (2025). PMID: 39019384

    L1bRCTCited in: Perioperative and Periprocedural Management
  41. [41]

    Schrickel JW, Beiert T, Linhart M et al.. Prevention of cerebral thromboembolism by oral anticoagulation with dabigatran after pulmonary vein isolation for atrial fibrillation: the ODIn-AF trial. Clinical research in cardiology : official journal of the German Cardiac Society (2024). PMID: 37921923

    L1bRCTCited in: Perioperative and Periprocedural Management
  42. [42]

    Providencia R, Ali H, Barra S et al.. Ablation of atrial fibrillation and risk of stroke: A meta-analysis. Heart rhythm (2026). PMID: 40398548

    L2aSR_OBSCited in: Perioperative and Periprocedural Management
  43. [43]

    Nakano T, Oka T, Okayama K et al.. Association between oral anticoagulants continuation on thromboembolism and bleeding events in patients with CHADS2 score 0-2 points after catheter ablation for persistent atrial fibrillation. Journal of cardiology (2025). PMID: 40287088

    L1bRCTCited in: Perioperative and Periprocedural Management
  44. [44]

    Lin AL, Allen K, Gutierrez JA et al.. Care for Atrial Fibrillation and Outcomes in Rural Versus Urban Communities in the United States: A Systematic and Narrative Review. Journal of the American Heart Association (2025). PMID: 40028844

    L2aSR_OBSCited in: Perioperative and Periprocedural Management
  45. [45]

    Sawalha K, Alakchar M, Mamas MA et al.. Safety of cardioversion without anticoagulation in patients' status post left atrial appendage occlusion: A systematic review and meta-analysis. Cardiovascular revascularization medicine : including molecular interventions (2026). PMID: 40877076

    L2aSR_OBSCited in: Perioperative and Periprocedural Management
  46. [46]

    Connolly SJ, Sharma M, Cohen AT et al.. Andexanet for Factor Xa Inhibitor-Associated Acute Intracerebral Hemorrhage. The New England journal of medicine (2024). PMID: 38749032

    L1bRCTCited in: Bleeding Management and Reversal Agents
  47. [47]

    Shahjouei S, Tsivgoulis G, Goyal N et al.. Safety of Intravenous Thrombolysis Among Patients Taking Direct Oral Anticoagulants: A Systematic Review and Meta-Analysis. Stroke (2020). PMID: 31884908

    L2aSR_OBSCited in: Bleeding Management and Reversal Agents
  48. [48]

    Katsanos AH, Schellinger PD, Köhrmann M et al.. Fatal oral anticoagulant-related intracranial hemorrhage: a systematic review and meta-analysis. European journal of neurology (2018). PMID: 29953696

    L2aSR_OBSCited in: Bleeding Management and Reversal Agents
  49. [49]

    Douketis JD, Spyropoulos AC. Perioperative Management of Patients Taking Direct Oral Anticoagulants: A Review. JAMA (2024). PMID: 39133476

    L5REVIEW_NARRATIVECited in: Bleeding Management and Reversal Agents
  50. [50]

    Costache RS, Dragomirică AS, Gheorghe BE et al.. Oral Anticoagulation in Patients with Chronic Liver Disease. Medicina (Kaunas, Lithuania) (2023). PMID: 36837547

    L5REVIEW_NARRATIVECited in: Bleeding Management and Reversal Agents
  51. [51]

    Crawley RM, Anderson RL. Prevention and Treatment of Bleeding with Direct Oral Anticoagulants. Drugs (2020). PMID: 32691292

    L5REVIEW_NARRATIVECited in: Bleeding Management and Reversal Agents
  52. [52]

    Rali P, Gangemi A, Moores A et al.. Direct-Acting Oral Anticoagulants in Critically Ill Patients. Chest (2019). PMID: 31251908

    L5REVIEW_NARRATIVECited in: Bleeding Management and Reversal Agents
  53. [53]

    Gerner ST, Huttner HB. Patients on NOACs in the Emergency Room. Current neurology and neuroscience reports (2019). PMID: 31144111

    L5REVIEW_NARRATIVECited in: Bleeding Management and Reversal Agents
  54. [54]

    Milling TJ, Ziebell CM. A review of oral anticoagulants, old and new, in major bleeding and the need for urgent surgery. Trends in cardiovascular medicine (2020). PMID: 30952383

    L5REVIEW_NARRATIVECited in: Bleeding Management and Reversal Agents
  55. [55]

    Leitch J, van Vlymen J. Managing the perioperative patient on direct oral anticoagulants. Canadian journal of anaesthesia = Journal canadien d'anesthesie (2017). PMID: 28429198

    L5REVIEW_NARRATIVECited in: Bleeding Management and Reversal Agents
  56. [56]

    Gangireddy SR, Halperin JL, Fuster V et al.. Percutaneous left atrial appendage closure for stroke prevention in patients with atrial fibrillation: an assessment of net clinical benefit. European heart journal (2012). PMID: 23008509

    L1bRCTCited in: Non-Pharmacologic Alternatives (LAAO)
  57. [57]

    Munkholm-Larsen S, Cao C, Yan TD et al.. Percutaneous atrial appendage occlusion for stroke prevention in patients with atrial fibrillation: a systematic review. Heart (British Cardiac Society) (2012). PMID: 22511532

    L2aSR_OBSCited in: Non-Pharmacologic Alternatives (LAAO)
  58. [58]

    Bode WD, Patel N, Gehi AK. Left atrial appendage occlusion for prevention of stroke in nonvalvular atrial fibrillation: a meta-analysis. Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing (2015). PMID: 25711953

    L2aSR_OBSCited in: Non-Pharmacologic Alternatives (LAAO)
  59. [59]

    Piccini JP, Sievert H, Patel MR. Left atrial appendage occlusion: rationale, evidence, devices, and patient selection. European heart journal (2017). PMID: 27628431

    L5REVIEW_NARRATIVECited in: Non-Pharmacologic Alternatives (LAAO)
  60. [60]

    Belgaid DR, Khan Z, Zaidi M et al.. Prospective randomized evaluation of the watchman left atrial appendage closure device in patients with atrial fibrillation versus long-term warfarin therapy: The PREVAIL trial. International journal of cardiology (2016). PMID: 27343417

    L5REVIEW_NARRATIVECited in: Non-Pharmacologic Alternatives (LAAO)
  61. [61]

    Jin Q, Yang J, Wu S et al.. Massive hemoptysis after left atrial appendage occlusion in a patient with atrial fibrillation and left atrial appendage thrombus: a case report. BMC cardiovascular disorders (2026). PMID: 41491151

    L4CASE_REPORTCited in: Non-Pharmacologic Alternatives (LAAO)
  62. [62]

    Alli O, Holmes D. Left atrial appendage occlusion. Heart (British Cardiac Society) (2015). PMID: 25518846

    L5REVIEW_NARRATIVECited in: Non-Pharmacologic Alternatives (LAAO)
  63. [63]

    Whitlock RP, Hanif H, Danter M. Nonpharmacologic approaches to stroke prevention in atrial fibrillation. The Canadian journal of cardiology (2013). PMID: 23790602

    L5REVIEW_NARRATIVECited in: Non-Pharmacologic Alternatives (LAAO)
  64. [64]

    Landmesser U, Holmes DR. Left atrial appendage closure: a percutaneous transcatheter approach for stroke prevention in atrial fibrillation. European heart journal (2012). PMID: 22041550

    L5REVIEW_NARRATIVECited in: Non-Pharmacologic Alternatives (LAAO)
  65. [65]

    Akella K, Yarlagadda B, Murtaza G et al.. Epicardial versus Endocardial Closure: Is One Better than the Other? Cardiac electrophysiology clinics (2020). PMID: 32067652

    L5REVIEW_NARRATIVECited in: Non-Pharmacologic Alternatives (LAAO)
  66. [66]

    Shahid S, Iqbal M, Shahabi M et al.. Factor XIa Inhibitors Versus Direct Oral Anticoagulants for Atrial Fibrillation: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Cardiovascular drugs and therapy (2026). PMID: 40560486

    L1aSR_MA_RCTCited in: Current Guidelines and Emerging Therapies
  67. [67]

    Campello E, Cappugi C, Catalani F et al.. Management of Anticoagulant Therapy in Athletes and Sportspeople: Italian Federation of Centers for Diagnosis and Surveillance of the Antithrombotic Therapies (FCSA) Position Paper. Thrombosis and haemostasis (2025). PMID: 40499916

    L1cGUIDELINECited in: Current Guidelines and Emerging Therapies
  68. [68]

    Carlin S, Cuker A, Gatt A et al.. Anticoagulation for stroke prevention in atrial fibrillation and treatment of venous thromboembolism and portal vein thrombosis in cirrhosis: guidance from the SSC of the ISTH. Journal of thrombosis and haemostasis : JTH (2024). PMID: 38823454

    L1cGUIDELINECited in: Current Guidelines and Emerging Therapies
  69. [69]

    Wang Y, Guo Y, Qin M et al.. 2024 Chinese Expert Consensus Guidelines on the Diagnosis and Treatment of Atrial Fibrillation in the Elderly, Endorsed by Geriatric Society of Chinese Medical Association (Cardiovascular Group) and Chinese Society of Geriatric Health Medicine (Cardiovascular Branch): Executive Summary. Thrombosis and haemostasis (2024). PMID: 38744425

    L1cGUIDELINECited in: Current Guidelines and Emerging Therapies
  70. [70]

    Chao TF, Joung B, Takahashi Y et al.. 2021 Focused Update Consensus Guidelines of the Asia Pacific Heart Rhythm Society on Stroke Prevention in Atrial Fibrillation: Executive Summary. Thrombosis and haemostasis (2022). PMID: 34773920

    L1cGUIDELINECited in: Current Guidelines and Emerging Therapies
  71. [71]

    Sulzgruber P, Wassmann S, Semb AG et al.. Oral anticoagulation in patients with non-valvular atrial fibrillation and a CHA2DS2-VASc score of 1: a current opinion of the European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy and European Society of Cardiology Council on Stroke. European heart journal. Cardiovascular pharmacotherapy (2019). PMID: 31119266

    L1cGUIDELINECited in: Current Guidelines and Emerging Therapies
  72. [72]

    Angiolillo DJ, Goodman SG, Bhatt DL et al.. Antithrombotic Therapy in Patients With Atrial Fibrillation Treated With Oral Anticoagulation Undergoing Percutaneous Coronary Intervention: A North American Perspective-2018 Update. Circulation (2018). PMID: 30571525

    L1cGUIDELINECited in: Current Guidelines and Emerging Therapies
  73. [73]

    Andrade JG, Verma A, Mitchell LB et al.. 2018 Focused Update of the Canadian Cardiovascular Society Guidelines for the Management of Atrial Fibrillation. The Canadian journal of cardiology (2018). PMID: 30404743

    L1cGUIDELINECited in: Current Guidelines and Emerging Therapies
  74. [74]

    Steffel J, Verhamme P, Potpara TS et al.. The 2018 European Heart Rhythm Association Practical Guide on the use of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation: executive summary. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology (2018). PMID: 29562331

    L1cGUIDELINECited in: Current Guidelines and Emerging Therapies
  75. [75]

    Angiolillo DJ, Goodman SG, Bhatt DL et al.. Antithrombotic Therapy in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention: A North American Perspective-2016 Update. Circulation. Cardiovascular interventions (2016). PMID: 27803042

    L1cGUIDELINECited in: Current Guidelines and Emerging Therapies

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